| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Sodium/hydrogen exchanger 3/H+ exchanger 3 (490-570 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC9A3 |
| Gene ID: | 6550 |
| Uniprot ID: | SL9A3_HUMAN |
| Immunogen Region: | 490-570 aa |
| Specificity: | SL9A3 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 490-570 |
| Function | Plasma membrane Na(+)/H(+) antiporter. Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis. Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation. |
| Protein Name | Sodium/Hydrogen Exchanger 3Na(+/H(+ Exchanger 3Nhe-3Solute Carrier Family 9 Member 3 |
| Database Links | Reactome: R-HSA-425986 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinCell MembraneRecycling Endosome MembraneEarly Endosome MembraneIn Intestinal Epithelial CellsLocalizes To The Ileal Brush BorderPhosphorylation At Ser-663 By Sgk1 Is Associated With Increased Abundance At The Cell MembraneAngiotensin-2 Enhances Apical Expression |
| Alternative Antibody Names | Anti-Sodium/Hydrogen Exchanger 3 antibodyAnti-Na(+/H(+ Exchanger 3 antibodyAnti-Nhe-3 antibodyAnti-Solute Carrier Family 9 Member 3 antibodyAnti-SLC9A3 antibodyAnti-NHE3 antibody |
Information sourced from Uniprot.org