| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SLC9A2 (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SLC9A2 |
| Gene ID: | 6549 |
| Uniprot ID: | SL9A2_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | Specific for SLC9A2. |
| Immunogen: | A synthetic peptide from c-terminal region of human SLC9A2 (Solute carrier family 9 member 2, NHE2) conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Plasma membrane Na(+)/H(+) antiporter. Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+). Major apical Na(+)/H(+) exchanger in the base of the colonic crypt. Controls in the colonic crypt intracellular pH (pHi) to direct colonic epithelial cell differentiation into the absorptive enterocyte lineage at the expense of the secretory lineage. |
| Protein Name | Sodium/Hydrogen Exchanger 2Na(+/H(+ Exchanger 2Nhe-2Solute Carrier Family 9 Member 2 |
| Database Links | Reactome: R-HSA-425986 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium/Hydrogen Exchanger 2 antibodyAnti-Na(+/H(+ Exchanger 2 antibodyAnti-Nhe-2 antibodyAnti-Solute Carrier Family 9 Member 2 antibodyAnti-SLC9A2 antibodyAnti-NHE2 antibody |
Information sourced from Uniprot.org