| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Y+L amino acid transporter 1L-type amino acid transporter 1 (239-289 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC7A7 |
| Gene ID: |
9056 |
| Uniprot ID: |
YLAT1_HUMAN |
| Immunogen Region: |
239-289 aa |
| Specificity: |
This antibody detects endogenous levels of human YLAT1 |
| Immunogen: |
Synthesized peptide derived from the human YLAT1 at the amino acid range 239-289 |
| Function | Heterodimer with SLC3A2, that functions as an antiporter which operates as an efflux route by exporting cationic amino acids from inside the cells in exchange with neutral amino acids plus sodium ions and may participate in nitric oxide synthesis via the transport of L-arginine. Also mediates arginine transport in non-polarized cells, such as monocytes, and is essential for the correct function of these cells. The transport mechanism is electroneutral and operates with a stoichiometry of 1:1. In vitro, Na(+) and Li(+), but also H(+), are cotransported with the neutral amino acids. |
| Protein Name | Y+L Amino Acid Transporter 1Monocyte Amino Acid Permease 2Mop-2Solute Carrier Family 7 Member 7Y(+L-Type Amino Acid Transporter 1Y+Lat1Y+Lat-1 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-352230Reactome: R-HSA-5660862 |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Y+L Amino Acid Transporter 1 antibodyAnti-Monocyte Amino Acid Permease 2 antibodyAnti-Mop-2 antibodyAnti-Solute Carrier Family 7 Member 7 antibodyAnti-Y(+L-Type Amino Acid Transporter 1 antibodyAnti-Y+Lat1 antibodyAnti-Y+Lat-1 antibodyAnti-SLC7A7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
