| Tissue Specificity | Expressed at high levels in the skeletal muscle, placenta and ovary. Expressed at intermediate levels in the liver and pancreas and at low levels in the kidney and heart. |
| Function | Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine).the affinity for its substrates differs between isoforms created by alternative splicing. May play a role in classical or alternative activation of macrophages via its role in arginine transport. Isoform 1: Functions as a permease that mediates the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). Shows a much higher affinity for L-arginine and L-homoarginine than isoform 2. Isoform 2: Functions as a low-affinity, high capacity permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). |
| Protein Name | Cationic Amino Acid Transporter 2Cat-2Cat2Low Affinity Cationic Amino Acid Transporter 2Solute Carrier Family 7 Member 2 |
| Database Links | Reactome: R-HSA-352230 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cationic Amino Acid Transporter 2 antibodyAnti-Cat-2 antibodyAnti-Cat2 antibodyAnti-Low Affinity Cationic Amino Acid Transporter 2 antibodyAnti-Solute Carrier Family 7 Member 2 antibodyAnti-SLC7A2 antibodyAnti-ATRC2 antibodyAnti-CAT2 antibody |
Information sourced from Uniprot.org
