Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SLC7A2 (642-658) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:100 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SLC7A2 |
Gene ID: |
6542 |
Uniprot ID: |
CTR2_HUMAN |
Immunogen Region: |
642-658 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 642-658 of human SLC7A2 (NP_001008539.3). |
Immunogen Sequence: |
PRNLSSPFIFHEKTSEF |
Tissue Specificity | Expressed at high levels in the skeletal muscle, placenta and ovary. Expressed at intermediate levels in the liver and pancreas and at low levels in the kidney and heart. |
Function | Functions as permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine).the affinity for its substrates differs between isoforms created by alternative splicing. May play a role in classical or alternative activation of macrophages via its role in arginine transport. Isoform 1: Functions as permease that mediates the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). Shows a much higher affinity for L-arginine and L-homoarginine than isoform 2. Isoform 2: Functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). |
Protein Name | Cationic Amino Acid Transporter 2Cat-2Cat2Low Affinity Cationic Amino Acid Transporter 2Solute Carrier Family 7 Member 2 |
Database Links | Reactome: R-HSA-352230 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Cationic Amino Acid Transporter 2 antibodyAnti-Cat-2 antibodyAnti-Cat2 antibodyAnti-Low Affinity Cationic Amino Acid Transporter 2 antibodyAnti-Solute Carrier Family 7 Member 2 antibodyAnti-SLC7A2 antibodyAnti-ATRC2 antibodyAnti-CAT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance