| Short Description : | Rabbit polyclonal anti-Solute carrier family 7 member 14 (50-100 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC7A14 |
| Gene ID: | 57709 |
| Uniprot ID: | S7A14_HUMAN |
| Immunogen: | Synthesized peptide derived from the human S7A14 at the amino acid range 50-100 |
| Immunogen Region: | 50-100 aa |
| Specificity: | This antibody detects endogenous levels of S7A14 at Human/Mouse |
| Function | Imports 4-aminobutanoate (GABA) into lysosomes. May act as a GABA sensor that regulates mTORC2-dependent INS signaling and gluconeogenesis. The transport mechanism and substrate selectivity remain to be elucidated. |
| Protein Name | Solute Carrier Family 7 Member 14Gamma-Aminobutyric Acid Transporter Slc7a14 |
| Database Links | |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane ProteinExhibits A Punctated Pattern In The CytoplasmWhich Partially Ovelaps With Lysosomes |
| Alternative Antibody Names | Anti-Solute Carrier Family 7 Member 14 antibodyAnti-Gamma-Aminobutyric Acid Transporter Slc7a14 antibodyAnti-SLC7A14 antibodyAnti-KIAA1613 antibody |
Information sourced from Uniprot.org
