| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human/Rat/Mouse/Marmoset |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SLC6A5 is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1: 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SLC6A5 |
| Gene ID: | 9152 |
| Uniprot ID: | SC6A5_HUMAN |
| Specificity: | Specific for SLC6A5. |
| Immunogen: | A synthetic peptide from human SLC6A5 conjugated to blue carrier protein was used as the antigen. |
| Post Translational Modifications | N-glycosylated. |
| Function | Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses. Isoform 2: Lacks sodium- and chloride-dependent glycine transporter activity. Isoform 3: Lacks sodium- and chloride-dependent glycine transporter activity. |
| Protein Name | Sodium- And Chloride-Dependent Glycine Transporter 2Glyt-2Glyt2Solute Carrier Family 6 Member 5 |
| Database Links | Reactome: R-HSA-442660Reactome: R-HSA-5619089 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium- And Chloride-Dependent Glycine Transporter 2 antibodyAnti-Glyt-2 antibodyAnti-Glyt2 antibodyAnti-Solute Carrier Family 6 Member 5 antibodyAnti-SLC6A5 antibodyAnti-GLYT2 antibodyAnti-NET1 antibody |
Information sourced from Uniprot.org