| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC6A5 (1-200) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC6A5 |
| Gene ID: |
9152 |
| Uniprot ID: |
SC6A5_HUMAN |
| Immunogen Region: |
1-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human SLC6A5 (NP_004202.3). |
| Immunogen Sequence: |
MDCSAPKEMNKLPANSPEAA AAQGHPDGPCAPRTSPEQEL PAAAAPPPPRVPRSASTGAQ TFQSADARACEAERPGVGSC KLSSPRAQAASAALRDLREA QGAQASPPPGSSGPGNALHC KIPFLRGPEGDANVSVGKGT LERNNTPVVGWVNMSQSTVV LGTDGITSVLPGSVATVATQ EDEQGDENKARGNWSSKLDF |
| Tissue Specificity | Expressed in medulla, and to a lesser extent in spinal cord and cerebellum. |
| Post Translational Modifications | N-glycosylated. |
| Function | Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses. Isoform 2: Lacks sodium- and chloride-dependent glycine transporter activity. Isoform 3: Lacks sodium- and chloride-dependent glycine transporter activity. |
| Protein Name | Sodium- And Chloride-Dependent Glycine Transporter 2Glyt-2Glyt2Solute Carrier Family 6 Member 5 |
| Database Links | Reactome: R-HSA-442660Reactome: R-HSA-5619089 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium- And Chloride-Dependent Glycine Transporter 2 antibodyAnti-Glyt-2 antibodyAnti-Glyt2 antibodyAnti-Solute Carrier Family 6 Member 5 antibodyAnti-SLC6A5 antibodyAnti-GLYT2 antibodyAnti-NET1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
