Tissue Specificity | Highly expressed in brain, fetal brain and salivary gland. Weakly expressed in other tissues. |
Function | Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption. May also act as a receptor for 4-hydroxybutyrate (Probable). (Microbial infection) In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A). |
Protein Name | Solute Carrier Family 52 - Riboflavin Transporter - Member 2Porcine Endogenous Retrovirus A Receptor 1Perv-A Receptor 1Protein Gpr172aRiboflavin Transporter 3Hrft3 |
Database Links | Reactome: R-HSA-196843 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Solute Carrier Family 52 - Riboflavin Transporter - Member 2 antibodyAnti-Porcine Endogenous Retrovirus A Receptor 1 antibodyAnti-Perv-A Receptor 1 antibodyAnti-Protein Gpr172a antibodyAnti-Riboflavin Transporter 3 antibodyAnti-Hrft3 antibodyAnti-SLC52A2 antibodyAnti-GPR172A antibodyAnti-PAR1 antibodyAnti-RFT3 antibody |
Information sourced from Uniprot.org