| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Electroneutral sodium bicarbonate exchanger 1-driven Cl-HCO3 exchanger (1012-1062) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC4A8 |
| Gene ID: | 9498 |
| Uniprot ID: | S4A8_HUMAN |
| Immunogen Region: | 1012-1062 |
| Specificity: | This antibody detects endogenous levels of human S4A8 |
| Immunogen: | Synthesized peptide derived from human S4A8 AA range: 1012-1062 |
| Function | Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. Mediates sodium reabsorption in the renal cortical collecting ducts. |
| Protein Name | Electroneutral Sodium Bicarbonate Exchanger 1Electroneutral Na(+-Driven Cl-Hco3 ExchangerSolute Carrier Family 4 Member 8K-Nbc3 |
| Database Links | Reactome: R-HSA-425381 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneCytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneIsoform 1: Cell MembraneIsoform 3: Cell MembraneIsoform 4: Cell MembraneIsoform 5: Cell Membrane |
| Alternative Antibody Names | Anti-Electroneutral Sodium Bicarbonate Exchanger 1 antibodyAnti-Electroneutral Na(+-Driven Cl-Hco3 Exchanger antibodyAnti-Solute Carrier Family 4 Member 8 antibodyAnti-K-Nbc3 antibodyAnti-SLC4A8 antibodyAnti-KIAA0739 antibodyAnti-NBC antibodyAnti-NBC3 antibodyAnti-NDCBE1 antibody |
Information sourced from Uniprot.org