Function | Proton-associated glucose and sucrose transporter. May be able to transport also fructose. Expressed at a late melanosome maturation stage where functions as proton/glucose exporter which increase lumenal pH by decreasing glycolysis. Regulates melanogenesis by maintaining melanosome neutralization that is initially initiated by transient OCA2 and required for a proper function of the tyrosinase TYR. |
Protein Name | Membrane-Associated Transporter ProteinMelanoma Antigen Aim1Protein Aim-1Solute Carrier Family 45 Member 2 |
Database Links | Reactome: R-HSA-5662702 |
Cellular Localisation | Melanosome MembraneMulti-Pass Membrane ProteinEnriched In Mature Melanocyte Membrane Subdomains |
Alternative Antibody Names | Anti-Membrane-Associated Transporter Protein antibodyAnti-Melanoma Antigen Aim1 antibodyAnti-Protein Aim-1 antibodyAnti-Solute Carrier Family 45 Member 2 antibodyAnti-SLC45A2 antibodyAnti-AIM1 antibodyAnti-MATP antibody |
Information sourced from Uniprot.org