| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SLC44A2 (2-100 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SLC44A2 |
| Gene ID: | 57153 |
| Uniprot ID: | CTL2_HUMAN |
| Immunogen Region: | 2-100 aa |
| Specificity: | Specific for SLC44A2. |
| Immunogen: | A synthetic peptide from aa region of 2-100 of human SLC44A2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
| Function | Isoform 1: Choline/H+ antiporter, mainly in mitochodria. Also acts as a low-affinity ethanolamine/H+ antiporter, regulating the supply of extracellular ethanolamine (Etn) for the CDP-Etn pathway, redistribute intracellular Etn and balance the CDP-Cho and CDP-Etn arms of the Kennedy pathway. Isoform 3: Does not exhibit choline transporter activity. |
| Protein Name | Choline Transporter-Like Protein 2Solute Carrier Family 44 Member 2 |
| Database Links | Reactome: R-HSA-1483191Reactome: R-HSA-425366Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinMitochondrion Outer MembraneMainly Expressed In Mitochondria |
| Alternative Antibody Names | Anti-Choline Transporter-Like Protein 2 antibodyAnti-Solute Carrier Family 44 Member 2 antibodyAnti-SLC44A2 antibodyAnti-CTL2 antibodyAnti-PSEC0210 antibody |
Information sourced from Uniprot.org
