• Western blot analysis of SLC39A9 Antibody. The lane on the right is blocked with the SLC39A9 peptide.
  • Western blot analysis of the lysates from HeLa cells using SLC39A9 antibody.
  • Western blot analysis of various cells using ZIP9 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Anti-SLC39A9 antibody (101-150 aa) (STJ96316)

SKU:
STJ96316

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Zinc transporter ZIP9 (101-150 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC39A9
Gene ID: 55334
Uniprot ID: S39A9_HUMAN
Immunogen Region: 101-150 aa
Specificity: ZIP9 Polyclonal Antibody detects endogenous levels of ZIP9 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human SLC39A9 at the amino acid range 101-150
Function Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Regulates intracellular zinc level, resulting in the enhancement of AKT1 and MAPK3/MAPK1 (Erk1/2) phosphorylation in response to the BCR activation. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. This pathway contributes to CLDN1 and CLDN5 expression and tight junction formation between adjacent Sertoli cells. Mediates androgen-induced vascular endothelial cell proliferation through activation of an inhibitory G protein leading to the AKT1 and MAPK3/MAPK1 (Erk1/2) activation which in turn modulate inhibition (phosphorylation) of GSK3B and CCND1 transcription. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
Protein Name Zinc Transporter Zip9
Solute Carrier Family 39 Member 9
Zrt- And Irt-Like Protein 9
Zip-9
Cellular Localisation Golgi Apparatus
Trans-Golgi Network Membrane
Cell Membrane
Multi-Pass Membrane Protein
Cytoplasm
Perinuclear Region
Mitochondrion
Nucleus
Alternative Antibody Names Anti-Zinc Transporter Zip9 antibody
Anti-Solute Carrier Family 39 Member 9 antibody
Anti-Zrt- And Irt-Like Protein 9 antibody
Anti-Zip-9 antibody
Anti-SLC39A9 antibody
Anti-ZIP9 antibody
Anti-UNQ714 antibody
Anti-PRO1377 antibody

Information sourced from Uniprot.org

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