Anti-SLC39A2 antibody (ECD) (STJ13102186)

SKU:
STJ13102186-100

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Host: Rabbit
Applications: IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SLC39A2 (ECD) is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Lyophilised
Purification: IgG purified
Dilution Range: IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage Instruction: Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol: SLC39A2
Gene ID: 29986
Uniprot ID: S39A2_HUMAN
Immunogen Region: ECD
Specificity: Specific for SLC39A2.
Immunogen: A synthetic peptide from extracellular domain of human Zinc transporter ZIP2 (SLC39A2, ZIP2) conjugated to an immunogenic carrier protein was used as the antigen.
Function Transporter for the divalent cation Zn(2+). Mediates the influx of Zn(2+) into cells from extracellular space. The Zn(2+) uniporter activity is independent of H(+)-driving force, but is modulated by extracellular pH and membrane potential. Transports also other divalent cations Zn(2+), Cd2(+), Cu2(+), Co2(+) in the order of decreasing affinity, respectively. In the skin, aids in the differentiation of keratinocytes in the epidermis.
Protein Name Zinc Transporter Zip2
6a1
Eti-1
Solute Carrier Family 39 Member 2
Zrt- And Irt-Like Protein 2
Zip-2
Hzip2
Database Links Reactome: R-HSA-442380
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Zinc Transporter Zip2 antibody
Anti-6a1 antibody
Anti-Eti-1 antibody
Anti-Solute Carrier Family 39 Member 2 antibody
Anti-Zrt- And Irt-Like Protein 2 antibody
Anti-Zip-2 antibody
Anti-Hzip2 antibody
Anti-SLC39A2 antibody
Anti-ZIP2 antibody

Information sourced from Uniprot.org

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