| Function | Zinc-influx transporter. When associated with SLC39A6, the heterodimer formed by SLC39A10 and SLC39A6 mediates cellular zinc uptake to trigger cells to undergo epithelial-to-mesenchymal transition (EMT). SLC39A10-SLC39A6 heterodimers play also an essentiel role in initiating mitosis by importing zinc into cells to initiate a pathway resulting in the onset of mitosis. Plays an important for both mature B-cell maintenance and humoral immune responses. When associated with SLC39A10, the heterodimer controls NCAM1 phosphorylation and integration into focal adhesion complexes during EMT. |
| Protein Name | Zinc Transporter Zip10Solute Carrier Family 39 Member 10Zrt- And Irt-Like Protein 10Zip-10 |
| Database Links | Reactome: R-HSA-442380 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneExpressed At The Apical Membranes Of Proximal Tubules In The Kidney |
| Alternative Antibody Names | Anti-Zinc Transporter Zip10 antibodyAnti-Solute Carrier Family 39 Member 10 antibodyAnti-Zrt- And Irt-Like Protein 10 antibodyAnti-Zip-10 antibodyAnti-SLC39A10 antibodyAnti-KIAA1265 antibodyAnti-ZIP10 antibody |
Information sourced from Uniprot.org
