| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Sodium-coupled neutral amino acid transporter 5 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC38A5 |
| Gene ID: |
92745 |
| Uniprot ID: |
S38A5_HUMAN |
| Specificity: |
This antibody detects endogenous levels of SLC38A5 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human SLC38A5 |
| Function | Symporter that cotransports neutral amino acids and sodium ions, coupled to an H(+) antiporter activity. Releases L-glutamine and glycine from astroglial cells and may participate in the glutamate/GABA-L-glutamine cycle and the NMDA receptors activation. In addition, contributes significantly to L-glutamine uptake in retina, namely in ganglion and Mueller cells therefore, participates in the retinal glutamate-glutamine cycle. The transport activity is pH sensitive and Li(+) tolerant. Moreover functions in both direction and is associated with large uncoupled fluxes of protons. The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+). May have a particular importance for modulation of net hepatic glutamine flux. |
| Protein Name | Sodium-Coupled Neutral Amino Acid Transporter 5Solute Carrier Family 38 Member 5System N Transporter 2 |
| Database Links | Reactome: R-HSA-352230 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalized At Astroglial Membrane |
| Alternative Antibody Names | Anti-Sodium-Coupled Neutral Amino Acid Transporter 5 antibodyAnti-Solute Carrier Family 38 Member 5 antibodyAnti-System N Transporter 2 antibodyAnti-SLC38A5 antibodyAnti-JM24 antibodyAnti-SN2 antibodyAnti-SNAT5 antibodyAnti-PP7194 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
