| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC37A4 |
| Gene ID: | 2542 |
| Uniprot ID: | G6PT1_HUMAN |
| Immunogen Region: | 415-429 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 330-429 of human SLC37A4 (NP_001458.1). |
| Immunogen Sequence: | WILVLGAVFGFSSYGPIALF GVIANESAPPNLCGTSHAIV GLMANVGGFLAGLPFSTIAK HYSWSTAFWVAEVICAASTA AFFLLRNIRTKMGRVSKKAE |
| Tissue Specificity | Mostly expressed in liver and kidney. |
| Function | Inorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum. Transports cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocates inorganic phosphate into the opposite direction. Forms with glucose-6-phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels. |
| Protein Name | Glucose-6-Phosphate Exchanger Slc37a4 Glucose-5-Phosphate Transporter Glucose-6-Phosphate Translocase Solute Carrier Family 37 Member 4 Transformation-Related Gene 19 Protein Trg-19 |
| Database Links | Reactome: R-HSA-3229133 Reactome: R-HSA-70263 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Glucose-6-Phosphate Exchanger Slc37a4 antibody Anti-Glucose-5-Phosphate Transporter antibody Anti-Glucose-6-Phosphate Translocase antibody Anti-Solute Carrier Family 37 Member 4 antibody Anti-Transformation-Related Gene 19 Protein antibody Anti-Trg-19 antibody Anti-SLC37A4 antibody Anti-G6PT antibody Anti-G6PT1 antibody Anti-PRO0685 antibody Anti-TRG19 antibody |
Information sourced from Uniprot.org