| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Nucleotide sugar transporter SLC35D1 (91-141 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC35D1 |
| Gene ID: |
23169 |
| Uniprot ID: |
S35D1_HUMAN |
| Immunogen Region: |
91-141 aa |
| Specificity: |
This antibody detects endogenous levels of S35D1 at Human |
| Immunogen: |
Synthesized peptide derived from the human S35D1 at the amino acid range 91-141 |
| Function | Antiporter that transports nucleotide sugars across the endoplasmic reticulum (ER) membrane in exchange for either their cognate nucleoside monophosphate or another nucleotide sugar. Transports various UDP-sugars including UDP-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc), UDP-N-acetyl-alpha-D-galactosamine (UDP-GalNAc) and UDP-alpha-D-glucuronate (UDP-GlcA), which are used by ER glucosyltransferases as sugar donors for the synthesis of sugar chains of glycoproteins, glycolipids and oligosaccharides. May couple UDP-GlcNAc or UDP-GalNAc efflux to UDP-GlcA influx into the ER lumen that in turn stimulates glucuronidation and subsequent excretion of endobiotics and xenobiotics. Plays a role in chondroitin sulfate biosynthesis, which is important for formation of cartilage extracellular matrix and normal skeletal development. |
| Protein Name | Nucleotide Sugar Transporter Slc35d1Solute Carrier Family 35 Member D1Udp-Galactose Transporter-Related Protein 7Ugtrel7Udp-Glucuronic Acid/Udp-N-Acetylgalactosamine TransporterUdp-Glca/Udp-Galnac Transporter |
| Database Links | Reactome: R-HSA-173599Reactome: R-HSA-5579020Reactome: R-HSA-727802 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Nucleotide Sugar Transporter Slc35d1 antibodyAnti-Solute Carrier Family 35 Member D1 antibodyAnti-Udp-Galactose Transporter-Related Protein 7 antibodyAnti-Ugtrel7 antibodyAnti-Udp-Glucuronic Acid/Udp-N-Acetylgalactosamine Transporter antibodyAnti-Udp-Glca/Udp-Galnac Transporter antibodyAnti-SLC35D1 antibodyAnti-KIAA0260 antibodyAnti-UGTREL7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
