| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein SLC31A2 (10-60 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC31A2 |
| Gene ID: |
1318 |
| Uniprot ID: |
COPT2_HUMAN |
| Immunogen Region: |
10-60 aa |
| Specificity: |
This antibody detects endogenous levels of COPT2 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human COPT2 at the amino acid range 10-60 |
| Post Translational Modifications | Ubiquitinated.ubiquitination and the subsequent proteasomal degradation are prevent by SLC31A1 that stabilizes it. |
| Function | Does not function as a copper(1+) importer in vivo. However, in vitro functions as low-affinity copper(1+) importer. Regulator of SLC31A1 which facilitates the cleavage of the SLC31A1 ecto-domain or which stabilizes the truncated form of SLC31A1 (Truncated CTR1 form), thereby drives the SLC31A1 truncated form-dependent endosomal copper export and modulates the copper and cisplatin accumulation via SLC31A1. |
| Protein Name | Protein Slc31a2Copper Transporter 2Hctr2Solute Carrier Family 31 Member 2 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembraneLate Endosome MembraneLysosome MembranePlasma Membrane Localization Is Partial |
| Alternative Antibody Names | Anti-Protein Slc31a2 antibodyAnti-Copper Transporter 2 antibodyAnti-Hctr2 antibodyAnti-Solute Carrier Family 31 Member 2 antibodyAnti-SLC31A2 antibodyAnti-COPT2 antibodyAnti-CTR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
