Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-SLC30A2 antibody (150-200 aa) (STJ96353)

SKU:
STJ96353
£48.00 - £252.00
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Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Proton-coupled zinc antiporter SLC30A2 (150-200 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC30A2
Gene ID: 7780
Uniprot ID: ZNT2_HUMAN
Immunogen Region: 150-200 aa
Specificity: ZnT-2 Polyclonal Antibody detects endogenous levels of ZnT-2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human SLC30A2 at the amino acid range 150-200
Function Isoform 1: Electroneutral proton-coupled antiporter concentrating zinc ions into a variety of intracellular organelles including endosomes, zymogen granules and mitochondria. Thereby, plays a crucial role in cellular zinc homeostasis to confer upon cells protection against its potential cytotoxicity. Regulates the zinc concentration of milk, through the transport of zinc ions into secretory vesicles of mammary cells. By concentrating zinc ions into lysosomes participates to lysosomal-mediated cell death during early mammary gland involution. Isoform 2: Electroneutral proton-coupled antiporter mediating the efflux of zinc ions through the plasma membrane.
Protein Name Proton-Coupled Zinc Antiporter Slc30a2
Solute Carrier Family 30 Member 2
Zinc Transporter 2
Znt-2
Database Links Reactome: R-HSA-435368
Cellular Localisation Isoform 1: Cytoplasmic Vesicle
Secretory Vesicle Membrane
Multi-Pass Membrane Protein
Zymogen Granule Membrane
Endosome Membrane
Lysosome Membrane
Mitochondrion Inner Membrane
Localization To Lysosomes Is Induced By Tnf-Alpha
Isoform 2: Cell Membrane
Alternative Antibody Names Anti-Proton-Coupled Zinc Antiporter Slc30a2 antibody
Anti-Solute Carrier Family 30 Member 2 antibody
Anti-Zinc Transporter 2 antibody
Anti-Znt-2 antibody
Anti-SLC30A2 antibody
Anti-ZNT2 antibody

Information sourced from Uniprot.org

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