| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Solute carrier family 2, facilitated glucose transporter member 8 (230-310 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC2A8 |
| Gene ID: | 29988 |
| Uniprot ID: | SL2A8_HUMAN |
| Immunogen Region: | 230-310 aa |
| Specificity: | GTR8 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 230-310 |
| Function | Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8 Glucose Transporter Type 8 Glut-8 Glucose Transporter Type X1 |
| Database Links | Reactome: R-HSA-189200 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Cytoplasmic Vesicle Membrane Principally Intracellular May Move Between Intracellular Vesicles And The Plasma Membrane The Dileucine Internalization Motif Is Critical For Intracellular Sequestration |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8 antibody Anti-Glucose Transporter Type 8 antibody Anti-Glut-8 antibody Anti-Glucose Transporter Type X1 antibody Anti-SLC2A8 antibody Anti-GLUT8 antibody Anti-GLUTX1 antibody |
Information sourced from Uniprot.org