• Western blot with Anti-SLC2A1 Antibody (STJ501193) of Rat brain at 1:2000 dilution in buffer on a 10% SDS gel.

Anti-SLC2A1 antibody (478-492) (STJ501193)

SKU:
STJ501193-100

£481.50
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Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SLC2A1 (478-492) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5 µg/µl
Dilution Range: WB: 1:5, 000
ELISA: 1:12, 000
IP: 1:200
IHC: 1:50-1:200
ICC: 1:50-1:200
IF: 1:50-1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SLC2A1
Gene ID: 6513
Uniprot ID: GTR1_HUMAN
Immunogen Region: 478-492
Immunogen: Synthetic peptide conjugated to KLH, corresponding to amino acids 478-492 of Human Glucose Transporter GLUT1. Peptide was covalently modified.
Tissue Specificity Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.
Post Translational Modifications Phosphorylation at Ser-226 by PKC promotes glucose uptake by increasing cell membrane localization.
Function Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity.can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation.
Protein Name Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1
Glucose Transporter Type 1 - Erythrocyte/Brain
Glut-1
Hepg2 Glucose Transporter
Database Links Reactome: R-HSA-189200
Reactome: R-HSA-196836
Reactome: R-HSA-422356
Reactome: R-HSA-5619043
Reactome: R-HSA-5653890
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Melanosome
Photoreceptor Inner Segment
Localizes Primarily At The Cell Surface
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Antibody Names Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1 antibody
Anti-Glucose Transporter Type 1 - Erythrocyte/Brain antibody
Anti-Glut-1 antibody
Anti-Hepg2 Glucose Transporter antibody
Anti-SLC2A1 antibody
Anti-GLUT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance