Post Translational Modifications | N-glycosylated. N-glycosylation is required for localization to the plasma membrane and the transporter activity. |
Function | Sodium and pyrimidine nucleoside symporter of the plasma membrane that imports uridine, thymidine and cytidine into cells by coupling their transport to the transmembrane sodium electrochemical gradient. Also transports adenosine, an atypical substrate transported with high apparent affinity, but low maximum velocity. Therefore, exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit). Involved in renal nucleoside (re)absorption. |
Protein Name | Sodium/Nucleoside Cotransporter 1Concentrative Nucleoside Transporter 1Cnt 1Hcnt1Na(+/Nucleoside Cotransporter 1Sodium-Coupled Nucleoside Transporter 1Solute Carrier Family 28 Member 1 |
Database Links | Reactome: R-HSA-83936 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
Alternative Antibody Names | Anti-Sodium/Nucleoside Cotransporter 1 antibodyAnti-Concentrative Nucleoside Transporter 1 antibodyAnti-Cnt 1 antibodyAnti-Hcnt1 antibodyAnti-Na(+/Nucleoside Cotransporter 1 antibodyAnti-Sodium-Coupled Nucleoside Transporter 1 antibodyAnti-Solute Carrier Family 28 Member 1 antibodyAnti-SLC28A1 antibodyAnti-CNT1 antibody |
Information sourced from Uniprot.org