| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Testis anion transporter 1 (82-132 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC26A8 |
| Gene ID: | 116369 |
| Uniprot ID: | S26A8_HUMAN |
| Immunogen Region: | 82-132 aa |
| Specificity: | This antibody detects endogenous levels of S26A8 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human S26A8 at the amino acid range 82-132 |
| Post Translational Modifications | N-glycosylated. |
| Function | Antiporter that mediates the exchange of sulfate and oxalate against chloride ions across a membrane. Stimulates anion transport activity of CFTR. May cooperate with CFTR in the regulation of chloride and bicarbonate ions fluxes required for activation of the ADCY10/PKA pathway during sperm motility and sperm capacitation. May play a role in sperm tail differentiation and motility and hence male fertility. |
| Protein Name | Testis Anion Transporter 1Anion Exchange TransporterSolute Carrier Family 26 Member 8 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinLocated At Both The Annulus And The Equatorial Segment Of The Human Sperm Head |
| Alternative Antibody Names | Anti-Testis Anion Transporter 1 antibodyAnti-Anion Exchange Transporter antibodyAnti-Solute Carrier Family 26 Member 8 antibodyAnti-SLC26A8 antibodyAnti-TAT1 antibody |
Information sourced from Uniprot.org