Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SLC26A4 |
Gene ID: |
5172 |
Uniprot ID: |
S26A4_HUMAN |
Immunogen Region: |
250-350 |
Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human SLC26A4 (NP_000432.1). |
Immunogen Sequence: |
VLSIIYTLVEIFQNIGDTNL ADFTAGLLTIVVCMAVKELN DRFRHKIPVPIPIEVIVTII ATAISYGANLEKNYNAGIVK SIPRGFLPPELPPVSLFSEM L |
Tissue Specificity | Highly expressed in the kidney (at protein level). High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues. |
Function | Sodium-independent transporter of chloride and iodide. Mediates electroneutral chloride-bicarbonate, chloride-iodide and chloride-formate exchange with 1:1 stoichiometry. Mediates electroneutral iodide-bicarbonate exchange. |
Protein Name | PendrinSodium-Independent Chloride/Iodide TransporterSolute Carrier Family 26 Member 4 |
Database Links | Reactome: R-HSA-427601Reactome: R-HSA-5619046 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
Alternative Antibody Names | Anti-Pendrin antibodyAnti-Sodium-Independent Chloride/Iodide Transporter antibodyAnti-Solute Carrier Family 26 Member 4 antibodyAnti-SLC26A4 antibodyAnti-PDS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance