Anti-SLC26A3 antibody (650-700) {Biotin} (STJ506234)

Name: Anti-SLC26A3 antibody (650-700) {Biotin} (STJ506234)
SKU: STJ506234-100
Price: 597 EUR
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationBiotin

IsotypeIgG

ImmunogenSynthetic peptide corresponding to amino acids within region 650-700 on human SCL26A3 protein.

STJ506234-100

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Short Description	Rabbit polyclonal antibody anti-SLC26A3 (650-700) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Applications	ELISA/IP/WB
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Biotin
Concentration	0.5-1.5 Mu g/Mu l
Purification	Affinity Purified
Dilution Range	WB: 1:500 ELISA: 1:10, 000 IP: 1:200 IHC: 1:50-1:100 ICC: 1:50-1:100 IF: 1:50-1:100
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	SLC26A3
Gene ID	1811
Uniprot ID	S26A3_HUMAN
Immunogen	Synthetic peptide corresponding to amino acids within region 650-700 on human SCL26A3 protein.
Immunogen Region	650-700

Tissue Specificity	Expressed in the colon. Expression is significantly decreased in adenomas (polyps) and adenocarcinomas of the colon.
Post Translational Modifications	N-glycosylation is required for efficient cell surface expression, and protection from proteolytic degradation.
Function	Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
Protein Name	Chloride Anion Exchanger Down-Regulated In Adenoma Protein Dra Solute Carrier Family 26 Member 3
Database Links	Reactome: R-HSA-427601 Reactome: R-HSA-5619085
Cellular Localisation	Apical Cell Membrane Multi-Pass Membrane Protein Membrane Cell Membrane Localized In Sperm Membranes Midpiece Of Sperm Tail Colocalizes With Cftr At The Midpiece Of Sperm Tail
Alternative Antibody Names	Anti-Chloride Anion Exchanger antibody Anti-Down-Regulated In Adenoma antibody Anti-Protein Dra antibody Anti-Solute Carrier Family 26 Member 3 antibody Anti-SLC26A3 antibody Anti-DRA antibody

Information sourced from Uniprot.org