Anti-SLC26A2 antibody (1-111) (STJ116772)

Name: Anti-SLC26A2 antibody (1-111) (STJ116772)
SKU: STJ116772
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ116772

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Short Description	Rabbit polyclonal SLC26A2 (1-111) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SLC26A2
Gene ID	1836
Uniprot ID	S26A2_HUMAN
Immunogen Region	1-111
Immunogen Sequence	MSSESKEQHNVSPRDSAEGN DSYPSGIHLELQRESSTDFK QFETNDQCRPYHRILIERQE KSDTNFKEFVIKKLQKNCQC SPAKAKNMILGFLPVLQWLP KYDLKKNILGD
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-111 of human SLC26A2 (NP_000103.2).

Tissue Specificity	Ubiquitously expressed.
Post Translational Modifications	N-glycosylated.
Function	Sulfate transporter which mediates sulfate uptake into chondrocytes in order to maintain adequate sulfation of proteoglycans which is needed for cartilage development. Mediates electroneutral anion exchange of sulfate ions for oxalate ions and of sulfate and oxalate ions for chloride ions. Mediates exchange of sulfate and oxalate ions for hydroxyl ions and of chloride ions for bromide, iodide and nitrate ions. The coupling of sulfate transport to both hydroxyl and chloride ions likely serves to ensure transport at both acidic pH when most sulfate uptake is mediated by sulfate-hydroxide exchange and alkaline pH when most sulfate uptake is mediated by sulfate-chloride exchange. Essential for chondrocyte proliferation, differentiation and cell size expansion.
Protein Name	Sulfate Transporter Diastrophic Dysplasia Protein Solute Carrier Family 26 Member 2
Database Links	Reactome: R-HSA-174362 Reactome: R-HSA-3560792 Reactome: R-HSA-427601
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Apical Cell Membrane
Alternative Antibody Names	Anti-Sulfate Transporter antibody Anti-Diastrophic Dysplasia Protein antibody Anti-Solute Carrier Family 26 Member 2 antibody Anti-SLC26A2 antibody Anti-DTD antibody Anti-DTDST antibody

Information sourced from Uniprot.org