• Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using SLC25A21 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HepG2 cells, using SLC25A21 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using ODC Polyclonal Antibody

Anti-SLC25A21 antibody (134-183) (STJ94601)

SKU:
STJ94601

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Mitochondrial 2-oxodicarboxylate carrier (134-183) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC25A21
Gene ID: 89874
Uniprot ID: ODC_HUMAN
Immunogen Region: 134-183
Specificity: ODC Polyclonal Antibody detects endogenous levels of ODC protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human SLC25A21. AA range:134-183
Tissue Specificity Expressed in placenta, gall bladder and colon.
Function Transports dicarboxylates across the inner membranes of mitochondria by a counter-exchange mechanism. Can transport 2-oxoadipate (2-oxohexanedioate), 2-oxoglutarate, adipate (hexanedioate), glutarate, and to a lesser extent, pimelate (heptanedioate), 2-oxopimelate (2-oxoheptanedioate), 2-aminoadipate (2-aminohexanedioate), oxaloacetate, and citrate. Plays a central role in catabolism of lysine, hydroxylysine, and tryptophan, by transporting common metabolite intermediates (such as 2-oxoadipate) into the mitochondria, where it is converted into acetyl-CoA and can enter the citric acid (TCA) cycle (Probable).
Protein Name Mitochondrial 2-Oxodicarboxylate Carrier
Odc
Mitochondrial 2-Oxoadipate Carrier
Solute Carrier Family 25 Member 21
Database Links Reactome: R-HSA-71064
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Mitochondrial 2-Oxodicarboxylate Carrier antibody
Anti-Odc antibody
Anti-Mitochondrial 2-Oxoadipate Carrier antibody
Anti-Solute Carrier Family 25 Member 21 antibody
Anti-SLC25A21 antibody
Anti-ODC antibody

Information sourced from Uniprot.org

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