| Function | Mediates the electroneutral exchange of acylcarnitines (O-acyl-(R)-carnitine or L-acylcarnitine) of different acyl chain lengths (ranging from O-acetyl-(R)-carnitine to long-chain O-acyl-(R)-carnitines) with free carnitine ((R)-carnitine or L-carnitine) across the mitochondrial inner membrane, via a ping-pong mechanism (Probable). Key player in the mitochondrial oxidation pathway, it translocates the fatty acids in the form of acylcarnitines into the mitochondrial matrix, where the carnitine palmitoyltransferase 2 (CPT-2) activates them to undergo fatty acid beta-oxidation (Probable). Catalyzes the unidirectional transport (uniport) of carnitine at lower rates than the antiport (exchange). |
| Protein Name | Mitochondrial Carnitine/Acylcarnitine Carrier ProteinCarnitine/Acylcarnitine TranslocaseCacCactSolute Carrier Family 25 Member 20 |
| Database Links | Reactome: R-HSA-200425 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Carnitine/Acylcarnitine Carrier Protein antibodyAnti-Carnitine/Acylcarnitine Translocase antibodyAnti-Cac antibodyAnti-Cact antibodyAnti-Solute Carrier Family 25 Member 20 antibodyAnti-SLC25A20 antibodyAnti-CAC antibodyAnti-CACT antibody |
Information sourced from Uniprot.org
