Anti-SLC25A12 antibody [R06-9E3] (STJA0034863)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human SLC25A12
General Information
| Short Description | Rabbit monoclonal anti-SLC25A12 for use in WB and IP in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-9E3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SLC25A12 |
| Gene ID | 8604 |
| Uniprot ID | S2512_HUMAN |
| Immunogen | A synthetic peptide of human SLC25A12 |
Additional Info
| Tissue Specificity | Expressed predominantly in the heart and skeletal muscle, weakly in brain and kidney. |
| Function | Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate (3-sulfino-L-alanine) by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. Lacks transport activity towards L-glutamine or gamma-aminobutyric acid (GABA). |
| Protein Name | Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - MitochondrialAraceli HiperlargaAralarAralar1Mitochondrial Aspartate Glutamate Carrier 1Solute Carrier Family 25 Member 12 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-8963693Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial antibodyAnti-Araceli Hiperlarga antibodyAnti-Aralar antibodyAnti-Aralar1 antibodyAnti-Mitochondrial Aspartate Glutamate Carrier 1 antibodyAnti-Solute Carrier Family 25 Member 12 antibodyAnti-SLC25A12 antibodyAnti-AGC1 antibodyAnti-ARALAR1 antibody |
Information sourced from Uniprot.org