Anti-SLC25A12 antibody (391-440 aa) (STJ91670)

SKU:
STJ91670
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (391-440 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC/IF/ELISA
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:SLC25A12
Gene ID:8604
Uniprot ID:S2512_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human CMC1 at the amino acid range 391-440
Immunogen Region:391-440 aa
Specificity:ARALAR Polyclonal Antibody detects endogenous levels of ARALAR protein.
Function Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate (3-sulfino-L-alanine) by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. Lacks transport activity towards L-glutamine or gamma-aminobutyric acid (GABA).
Protein Name Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial
Araceli Hiperlarga
Aralar
Aralar1
Mitochondrial Aspartate Glutamate Carrier 1
Solute Carrier Family 25 Member 12
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-8963693
Reactome: R-HSA-9856872
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial antibody
Anti-Araceli Hiperlarga antibody
Anti-Aralar antibody
Anti-Aralar1 antibody
Anti-Mitochondrial Aspartate Glutamate Carrier 1 antibody
Anti-Solute Carrier Family 25 Member 12 antibody
Anti-SLC25A12 antibody
Anti-AGC1 antibody
Anti-ARALAR1 antibody

Information sourced from Uniprot.org