Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (391-440 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SLC25A12 |
Gene ID: |
8604 |
Uniprot ID: |
S2512_HUMAN |
Immunogen Region: |
391-440 aa |
Specificity: |
ARALAR Polyclonal Antibody detects endogenous levels of ARALAR protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human CMC1 at the amino acid range 391-440 |
Function | Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. |
Protein Name | Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - MitochondrialAraceli HiperlargaAralarAralar1Mitochondrial Aspartate Glutamate Carrier 1Solute Carrier Family 25 Member 12 |
Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-70263Reactome: R-HSA-8963693 |
Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial antibodyAnti-Araceli Hiperlarga antibodyAnti-Aralar antibodyAnti-Aralar1 antibodyAnti-Mitochondrial Aspartate Glutamate Carrier 1 antibodyAnti-Solute Carrier Family 25 Member 12 antibodyAnti-SLC25A12 antibodyAnti-AGC1 antibodyAnti-ARALAR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance