| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (391-440 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC25A12 |
| Gene ID: | 8604 |
| Uniprot ID: | S2512_HUMAN |
| Immunogen Region: | 391-440 aa |
| Specificity: | ARALAR Polyclonal Antibody detects endogenous levels of ARALAR protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CMC1 at the amino acid range 391-440 |
| Function | Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. |
| Protein Name | Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial Araceli Hiperlarga Aralar Aralar1 Mitochondrial Aspartate Glutamate Carrier 1 Solute Carrier Family 25 Member 12 |
| Database Links | Reactome: R-HSA-1268020 Reactome: R-HSA-8963693 Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion Inner Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial antibody Anti-Araceli Hiperlarga antibody Anti-Aralar antibody Anti-Aralar1 antibody Anti-Mitochondrial Aspartate Glutamate Carrier 1 antibody Anti-Solute Carrier Family 25 Member 12 antibody Anti-SLC25A12 antibody Anti-AGC1 antibody Anti-ARALAR1 antibody |
Information sourced from Uniprot.org