Anti-SLC24A1 antibody (800-850 aa) (STJ13102230)

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STJ13102230-100
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Short Description :Rabbit polyclonal anti-SLC24A1 (800-850 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/WB
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Purification:IgG purified
Dilution Range:IHC, WB. A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Formulation:Lyophilised
Storage Instruction:Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol:SLC24A1
Gene ID:9187
Uniprot ID:NCKX1_HUMAN
Immunogen:A synthetic peptide from aa region of 800-850 of human SLC24A1 conjugated to an immunogenic carrier protein was used as the antigen.
Immunogen Region:800-850 aa
Specificity:Specific for SLC24A1.
Post Translational Modifications The uncleaved signal sequence is required for efficient membrane targeting and proper membrane integration.
Function Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation.
Protein Name Sodium/Potassium/Calcium Exchanger 1
Na(+/K(+/Ca(2+-Exchange Protein 1
Retinal Rod Na-Ca+K Exchanger
Solute Carrier Family 24 Member 1
Database Links Reactome: R-HSA-2485179
Reactome: R-HSA-425561
Reactome: R-HSA-5619077
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Sodium/Potassium/Calcium Exchanger 1 antibody
Anti-Na(+/K(+/Ca(2+-Exchange Protein 1 antibody
Anti-Retinal Rod Na-Ca+K Exchanger antibody
Anti-Solute Carrier Family 24 Member 1 antibody
Anti-SLC24A1 antibody
Anti-KIAA0702 antibody
Anti-NCKX1 antibody

Information sourced from Uniprot.org

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