Anti-SLC1A7 antibody (480-560) (STJ11105496)

SKU:
STJ11105496
£112.50 - £524.50
Processing The item has been added

Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC1A7
Gene ID: 6512
Uniprot ID: EAA5_HUMAN
Immunogen Region: 480-560
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 480-560 of human SLC1A7 (NP_006662.3).
Immunogen Sequence: DFARDTGTEKLLPCETKPVS LQEIVAAQQNGCVKSVAEAS ELTLGPTCPHHVPVQVEQDE ELPAASLNHCTIQISELETN V
Tissue Specificity Expressed primarily in retina. Detectable in liver, heart, muscle and brain.
Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Acts primarily as an inhibitory glutamate-gated chloride channel being a major inhibitory presynaptic receptor at mammalian rod bipolar cell axon terminals. Glutamate binding gates a large Cl(-) conductance that mediates inhibition, affecting visual processing in the retina.
Protein Name Excitatory Amino Acid Transporter 5
Retinal Glutamate Transporter
Solute Carrier Family 1 Member 7
Database Links Reactome: R-HSA-210500
Reactome: R-HSA-425393
Cellular Localisation Photoreceptor Inner Segment Membrane
Multi-Pass Membrane Protein
Synaptic Cell Membrane
Located In Both Cone And Rod Photoreceptor Terminals And In Axon Terminals Of Rod Bipolar Cells
Alternative Antibody Names Anti-Excitatory Amino Acid Transporter 5 antibody
Anti-Retinal Glutamate Transporter antibody
Anti-Solute Carrier Family 1 Member 7 antibody
Anti-SLC1A7 antibody
Anti-EAAT5 antibody

Information sourced from Uniprot.org