| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC1A6 (155-265) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC1A6 |
| Gene ID: |
6511 |
| Uniprot ID: |
EAA4_HUMAN |
| Immunogen Region: |
155-265 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 155-265 of human SLC1A6 (NP_001259016.1). |
| Immunogen Sequence: |
PGKGSKEGLHREGRIETIPT ADAFMDLIRNMFPPNLVEAC FKQFKTQYSTRVVTRTMVRT ENGSEPGASMPPPFSVENGT SFLENVTRALGTLQEMLSFE ETVPVPGSANG |
| Tissue Specificity | Brain, mainly in the cerebellum. Expressed densely and selectively in cell bodies of Purkinje cells. |
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable). |
| Protein Name | Excitatory Amino Acid Transporter 4Sodium-Dependent Glutamate/Aspartate TransporterSolute Carrier Family 1 Member 6 |
| Database Links | Reactome: R-HSA-210500Reactome: R-HSA-425393 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Excitatory Amino Acid Transporter 4 antibodyAnti-Sodium-Dependent Glutamate/Aspartate Transporter antibodyAnti-Solute Carrier Family 1 Member 6 antibodyAnti-SLC1A6 antibodyAnti-EAAT4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
