Anti-SLC1A3 antibody (C-Term) (STJ13100123)

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STJ13100123-500
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Host: Rabbit
Applications: IHC/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-SLC1A3 (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Lyophilised
Purification: IgG purified
Dilution Range: IHC, WB. A concentration of 10-50 ug/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Storage Instruction: Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol: Slc1a3
Gene ID: 20512
Uniprot ID: EAA1_MOUSE
Immunogen Region: C-Term
Specificity: Specific for EAAT1.
Immunogen: A synthetic peptide from c-terminal region of mouse EAAT1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat.
Post Translational Modifications Glycosylated.
Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate.
Protein Name Excitatory Amino Acid Transporter 1
Glial High Affinity Glutamate Transporter
High-Affinity Neuronal Glutamate Transporter
Glut-1
Sodium-Dependent Glutamate/Aspartate Transporter 1
Glast-1
Solute Carrier Family 1 Member 3
Database Links Reactome: R-MMU-210455
Reactome: -MMU-210500
Reactome: -MMU-425393
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Excitatory Amino Acid Transporter 1 antibody
Anti-Glial High Affinity Glutamate Transporter antibody
Anti-High-Affinity Neuronal Glutamate Transporter antibody
Anti-Glut-1 antibody
Anti-Sodium-Dependent Glutamate/Aspartate Transporter 1 antibody
Anti-Glast-1 antibody
Anti-Solute Carrier Family 1 Member 3 antibody
Anti-Slc1a3 antibody
Anti-Eaat1 antibody
Anti-Gmt1 antibody

Information sourced from Uniprot.org

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