Anti-SLC17A3 antibody (370-420 aa) (STJ13102285)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 370-420 of human SLC17A3 conjugated to blue carrier protein was used as the antigen. The peptide shares 94% identity with mouse sequence.
General Information
| Short Description | Rabbit polyclonal anti-SLC17A3 (370-420 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SLC17A3 |
| Gene ID | 10786 |
| Uniprot ID | NPT4_HUMAN |
| Immunogen | A synthetic peptide from aa region 370-420 of human SLC17A3 conjugated to blue carrier protein was used as the antigen. The peptide shares 94% identity with mouse sequence. |
| Immunogen Region | 370-420 aa |
| Specificity | Specific for SLC17A3. |
Additional Info
| Function | Isoform 2: Transports organic anions in a voltage-driven, multispecific, manner, on the apical side of renal proximal tubule. In particular, participates in the secretion of urate from the cell into the lumen. Urate is the end product of purine metabolism. May have roles in the metabolism and secretion of estrone sulfate, estradiol-17-beta-glucuronide, ochratoxin A, as wells as drugs such as bumetanide. |
| Protein Name | Sodium-Dependent Phosphate Transport Protein 4Na(+/Pi Cotransporter 4Npt4Sodium/Phosphate Cotransporter 4Solute Carrier Family 17 Member 3 |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Isoform 1: Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinIsoform 2: Cell Membrane |
| Alternative Antibody Names | Anti-Sodium-Dependent Phosphate Transport Protein 4 antibodyAnti-Na(+/Pi Cotransporter 4 antibodyAnti-Npt4 antibodyAnti-Sodium/Phosphate Cotransporter 4 antibodyAnti-Solute Carrier Family 17 Member 3 antibodyAnti-SLC17A3 antibodyAnti-NPT4 antibody |
Information sourced from Uniprot.org