Anti-SLC12A4 antibody (658-708 aa) (STJ197335)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide derived from SLC12A4 at the amino acid range 658-708
General Information
| Short Description | Rabbit polyclonal anti-Solute carrier family 12 member 4 (658-708 aa) for use in WB, IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000IHC 1:100-200IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC12A4 |
| Gene ID | 6560 |
| Uniprot ID | S12A4_HUMAN |
| Immunogen | Synthetic peptide derived from SLC12A4 at the amino acid range 658-708 |
| Immunogen Region | 658-708 aa |
| Specificity | SLC12A4 protein (A248) detects endogenous levels of SLC12A4 |
Additional Info
| Post Translational Modifications | Phosphorylated, phosphorylation may regulate transporter activity. |
| Function | Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia. Isoform 4: No transporter activity. |
| Protein Name | Solute Carrier Family 12 Member 4Electroneutral Potassium-Chloride Cotransporter 1Erythroid K-Cl Cotransporter 1Hkcc1 |
| Database Links | Reactome: R-HSA-426117 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Solute Carrier Family 12 Member 4 antibodyAnti-Electroneutral Potassium-Chloride Cotransporter 1 antibodyAnti-Erythroid K-Cl Cotransporter 1 antibodyAnti-Hkcc1 antibodyAnti-SLC12A4 antibodyAnti-KCC1 antibody |
Information sourced from Uniprot.org