Anti-SLC10A2 antibody (280-335 aa) (STJ13102228)

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STJ13102228-100
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Host: Rabbit
Applications: IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-SLC10A2 (280-335 aa) is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Lyophilised
Purification: IgG purified
Dilution Range: IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage Instruction: Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol: SLC10A2
Gene ID: 6555
Uniprot ID: NTCP2_HUMAN
Immunogen Region: 280-335 aa
Specificity: Specific for SLC10A2.
Immunogen: A synthetic peptide from aa region 280-335 of human SLC10A2 conjugated to an immunogenic carrier protein was used as the antigen.
Function Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation.
Protein Name Ileal Sodium/Bile Acid Cotransporter
Apical Sodium-Dependent Bile Acid Transporter
Asbt
Ileal Na(+/Bile Acid Cotransporter
Ileal Sodium-Dependent Bile Acid Transporter
Ibat
Isbt
Na(+-Dependent Ileal Bile Acid Transporter
Sodium/Taurocholate Cotransporting Polypeptide - Ileal
Solute Carrier Family 10 Member 2
Database Links Reactome: R-HSA-159418
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Ileal Sodium/Bile Acid Cotransporter antibody
Anti-Apical Sodium-Dependent Bile Acid Transporter antibody
Anti-Asbt antibody
Anti-Ileal Na(+/Bile Acid Cotransporter antibody
Anti-Ileal Sodium-Dependent Bile Acid Transporter antibody
Anti-Ibat antibody
Anti-Isbt antibody
Anti-Na(+-Dependent Ileal Bile Acid Transporter antibody
Anti-Sodium/Taurocholate Cotransporting Polypeptide - Ileal antibody
Anti-Solute Carrier Family 10 Member 2 antibody
Anti-SLC10A2 antibody
Anti-ASBT antibody
Anti-ISBT antibody
Anti-NTCP2 antibody

Information sourced from Uniprot.org

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