Tissue Specificity | Specifically expressed in epidermis and cultured keratinocytes. |
Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation. The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues. |
Protein Name | Pou Domain - Class 2 - Transcription Factor 3Octamer-Binding Protein 11Oct-11Octamer-Binding Transcription Factor 11Otf-11Transcription Factor Pla-1Transcription Factor Skn-1 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Pou Domain - Class 2 - Transcription Factor 3 antibodyAnti-Octamer-Binding Protein 11 antibodyAnti-Oct-11 antibodyAnti-Octamer-Binding Transcription Factor 11 antibodyAnti-Otf-11 antibodyAnti-Transcription Factor Pla-1 antibodyAnti-Transcription Factor Skn-1 antibodyAnti-POU2F3 antibodyAnti-OTF11 antibodyAnti-PLA1 antibody |
Information sourced from Uniprot.org