Anti-Skn1 antibody (150-200) {FITC} (STJ506336)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide corresponding to amino acids within region 150-200 on human POU2F3 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-Skn1 (150-200) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Concentration | 0.5-1.5 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | ELISA 1:10, 000IP 1:200WB 1:500 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | POU2F3 |
| Gene ID | 25833 |
| Uniprot ID | PO2F3_HUMAN |
| Immunogen | Synthetic peptide corresponding to amino acids within region 150-200 on human POU2F3 protein. |
| Immunogen Region | 150-200 |
Additional Info
| Tissue Specificity | Specifically expressed in epidermis and cultured keratinocytes. |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation. The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues. |
| Protein Name | Pou Domain - Class 2 - Transcription Factor 3Octamer-Binding Protein 11Oct-11Octamer-Binding Transcription Factor 11Otf-11Transcription Factor Pla-1Transcription Factor Skn-1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 2 - Transcription Factor 3 antibodyAnti-Octamer-Binding Protein 11 antibodyAnti-Oct-11 antibodyAnti-Octamer-Binding Transcription Factor 11 antibodyAnti-Otf-11 antibodyAnti-Transcription Factor Pla-1 antibodyAnti-Transcription Factor Skn-1 antibodyAnti-POU2F3 antibodyAnti-OTF11 antibodyAnti-PLA1 antibody |
Information sourced from Uniprot.org