Anti-SKIV2L antibody (1-140 aa) (STJ11105979)

SKU:
STJ11105979
£112.50 - £524.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: SKIC2
Gene ID: 6499
Uniprot ID: SKI2_HUMAN
Immunogen Region: 1-140 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SKIV2L (NP_008860.4).
Immunogen Sequence: MMETERLVLPPPDPLDLPLR AVELGCTGHWELLNLPGAPE SSLPHGLPPCAPDLQQEAEQ LFLSSPAWLPLHGVEHSARK WQRKTDPWSLLAVLGAPVPS DLQAQRHPTTGQILGYKEVL LENTNLSATTSLSLRRPPGP
Function Helicase component of the SKI complex, a multiprotein complex that assists the RNA-degrading exosome during the mRNA decay and quality-control pathways. The SKI complex catalyzes mRNA extraction from 80S ribosomal complexes in the 3'-5' direction and channels mRNA to the cytosolic exosome for degradation. SKI-mediated extraction of mRNA from stalled ribosomes allow binding of the Pelota-HBS1L complex and subsequent ribosome disassembly by ABCE1 for ribosome recycling. In the nucleus, the SKI complex associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C).
Protein Name Superkiller Complex Protein 2
Ski2
Helicase-Like Protein
Hlp
Database Links Reactome: R-HSA-390471
Reactome: R-HSA-429958
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Superkiller Complex Protein 2 antibody
Anti-Ski2 antibody
Anti-Helicase-Like Protein antibody
Anti-Hlp antibody
Anti-SKIC2 antibody
Anti-DDX13 antibody
Anti-SKI2W antibody
Anti-SKIV2 antibody
Anti-SKIV2L antibody
Anti-W antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ11106497 Anti-IMPACT antibody (1-140 aa) (STJ11106497) Rabbit Polyclonal Human WB/ELISA
STJ11104043 Anti-SD1 antibody (1-140 aa) (STJ11104043) Rabbit Polyclonal O.sativa WB/ELISA
STJ11106072 Anti-ZC3H12A antibody (1-140 aa) (STJ11106072) Rabbit Polyclonal Mouse WB/ELISA
STJ11104067 Anti-Chalk5 antibody (1-140 aa) (STJ11104067) Rabbit Polyclonal O.sativa WB/ELISA
STJ197961 Anti-ERVV-1 antibody (140-190 aa) (STJ197961) Rabbit Polyclonal Human/Rat/Mouse WB
!