| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SKAP2 (1-120) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SKAP2 |
| Gene ID: |
8935 |
| Uniprot ID: |
SKAP2_HUMAN |
| Immunogen Region: |
1-120 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SKAP2 (NP_003921.2). |
| Immunogen Sequence: |
MPNPSSTSSPYPLPEEIRNL LADVETFVADILKGENLSKK AKEKRESLIKKIKDVKSIYL QEFQDKGDAEDGEEYDDPFA GPPDTISLASERYDKDDEAP SDGAQFPPIAAQDLPFVLKA |
| Tissue Specificity | Ubiquitously expressed. Present in platelets (at protein level). |
| Post Translational Modifications | Phosphorylated in resting platelets. Phosphorylated by FYN on Tyr-261 upon T-cell activation (Probable). Dephosphorylated on Tyr-75 by PTPN22. |
| Function | May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway. |
| Protein Name | Src Kinase-Associated Phosphoprotein 2Pyk2/Raftk-Associated ProteinRetinoic Acid-Induced Protein 70Skap55 HomologSkap-55homSkap-HomSrc Family-Associated Phosphoprotein 2Src Kinase-Associated Phosphoprotein 55-Related ProteinSrc-Associated Adapter Protein With Ph And Sh3 Domains |
| Database Links | Reactome: R-HSA-391160 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Src Kinase-Associated Phosphoprotein 2 antibodyAnti-Pyk2/Raftk-Associated Protein antibodyAnti-Retinoic Acid-Induced Protein 70 antibodyAnti-Skap55 Homolog antibodyAnti-Skap-55hom antibodyAnti-Skap-Hom antibodyAnti-Src Family-Associated Phosphoprotein 2 antibodyAnti-Src Kinase-Associated Phosphoprotein 55-Related Protein antibodyAnti-Src-Associated Adapter Protein With Ph And Sh3 Domains antibodyAnti-SKAP2 antibodyAnti-PRAP antibodyAnti-RA70 antibodyAnti-SAPS antibodyAnti-SCAP2 antibodyAnti-SKAP55R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
