Anti-SKAP2 antibody (1-120) (STJ118195)

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STJ118195
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Short Description :Rabbit polyclonal SKAP2 (1-120) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:SKAP2
Gene ID:8935
Uniprot ID:SKAP2_HUMAN
Immunogen Region:1-120
Immunogen Sequence:MPNPSSTSSPYPLPEEIRNL LADVETFVADILKGENLSKK AKEKRESLIKKIKDVKSIYL QEFQDKGDAEDGEEYDDPFA GPPDTISLASERYDKDDEAP SDGAQFPPIAAQDLPFVLKA
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SKAP2 (NP_003921.2).
Tissue Specificity Ubiquitously expressed. Present in platelets (at protein level).
Post Translational Modifications Phosphorylated in resting platelets. Phosphorylated by FYN on Tyr-261 upon T-cell activation (Probable). Dephosphorylated on Tyr-75 by PTPN22.
Function May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.
Protein Name Src Kinase-Associated Phosphoprotein 2
Pyk2/Raftk-Associated Protein
Retinoic Acid-Induced Protein 70
Skap55 Homolog
Skap-55hom
Skap-Hom
Src Family-Associated Phosphoprotein 2
Src Kinase-Associated Phosphoprotein 55-Related Protein
Src-Associated Adapter Protein With Ph And Sh3 Domains
Database Links Reactome: R-HSA-391160
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Src Kinase-Associated Phosphoprotein 2 antibody
Anti-Pyk2/Raftk-Associated Protein antibody
Anti-Retinoic Acid-Induced Protein 70 antibody
Anti-Skap55 Homolog antibody
Anti-Skap-55hom antibody
Anti-Skap-Hom antibody
Anti-Src Family-Associated Phosphoprotein 2 antibody
Anti-Src Kinase-Associated Phosphoprotein 55-Related Protein antibody
Anti-Src-Associated Adapter Protein With Ph And Sh3 Domains antibody
Anti-SKAP2 antibody
Anti-PRAP antibody
Anti-RA70 antibody
Anti-SAPS antibody
Anti-SCAP2 antibody
Anti-SKAP55R antibody

Information sourced from Uniprot.org