| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Homeobox protein SIX5 (201-250 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SIX5 |
| Gene ID: | 147912 |
| Uniprot ID: | SIX5_HUMAN |
| Immunogen Region: | 201-250 aa |
| Specificity: | Six5 Polyclonal Antibody detects endogenous levels of Six5 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human SIX5 at the amino acid range 201-250 |
| Function | Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCAAGAGTTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter. Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3. |
| Protein Name | Homeobox Protein Six5Dm Locus-Associated Homeodomain ProteinSine Oculis Homeobox Homolog 5 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Six5 antibodyAnti-Dm Locus-Associated Homeodomain Protein antibodyAnti-Sine Oculis Homeobox Homolog 5 antibodyAnti-SIX5 antibodyAnti-DMAHP antibody |
Information sourced from Uniprot.org