| Short Description : | Rabbit polyclonal anti-Apoptosis regulatory protein Siva (1-50 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SIVA1 |
| Gene ID: | 10572 |
| Uniprot ID: | SIVA_HUMAN |
| Immunogen: | Synthesized peptide derived from part of the human protein at the amino acid range 1-50 |
| Immunogen Region: | 1-50 aa |
| Specificity: | SIVA Polyclonal Antibody detects endogenous levels of protein. |
| Post Translational Modifications | Phosphorylated by ABL2/ARG in response to oxidative stress. |
| Function | Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. |
| Protein Name | Apoptosis Regulatory Protein SivaCd27-Binding ProteinCd27bp |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusIn The NucleusAccumulates In Dot-Like Structures |
| Alternative Antibody Names | Anti-Apoptosis Regulatory Protein Siva antibodyAnti-Cd27-Binding Protein antibodyAnti-Cd27bp antibodyAnti-SIVA1 antibodyAnti-SIVA antibody |
Information sourced from Uniprot.org
