| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Signal-induced proliferation-associated protein 1 (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SIPA1 |
| Gene ID: | 6494 |
| Uniprot ID: | SIPA1_HUMAN |
| Immunogen Region: | N-Term |
| Specificity: | This antibody detects endogenous levels of SIPA1 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human N-ternal SIPA1 |
| Function | GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state. Affects cell cycle progression. |
| Protein Name | Signal-Induced Proliferation-Associated Protein 1Sipa-1Gtpase-Activating Protein Spa-1P130 Spa-1 |
| Database Links | Reactome: R-HSA-392517 |
| Cellular Localisation | NucleusCytoplasmPerinuclear RegionEndomembrane SystemPeripheral Membrane ProteinMostly Localized In The Perinuclear Membraneous Region |
| Alternative Antibody Names | Anti-Signal-Induced Proliferation-Associated Protein 1 antibodyAnti-Sipa-1 antibodyAnti-Gtpase-Activating Protein Spa-1 antibodyAnti-P130 Spa-1 antibodyAnti-SIPA1 antibodyAnti-SPA1 antibody |
Information sourced from Uniprot.org