| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SIGLECL1 (C-Term) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Preliminary experiments gave no signal but low background in Human PBMC and Molt-4 lysates at up to 1µg/ml. We would appreciate any feedback from people in the field-have any results |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SIGLEC12 |
| Gene ID: | 89858 |
| Uniprot ID: | SIG12_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_201586.1; NP_443729.1 |
| Specificity: | This antibody is expected to recognise both human isoforms of this protein (NP_201586.1; NP_443729.1). |
| Immunogen Sequence: | EAIGYEYSEINIPK |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 12Siglec-12Sialic Acid-Binding Ig-Like Lectin-Like 1Siglec-L1 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Sialic Acid-Binding Ig-Like Lectin 12 antibodyAnti-Siglec-12 antibodyAnti-Sialic Acid-Binding Ig-Like Lectin-Like 1 antibodyAnti-Siglec-L1 antibodyAnti-SIGLEC12 antibodyAnti-SIGLECL1 antibodyAnti-SLG antibodyAnti-UNQ9215 antibodyAnti-PRO34042 antibody |
Information sourced from Uniprot.org