| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SIGLEC12 |
| Gene ID: |
89858 |
| Uniprot ID: |
SIG12_HUMAN |
| Immunogen Region: |
20-210 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 20-210 of human SIGLEC12 (NP_443729.1). |
| Immunogen Sequence: |
EQKDYLLTMQKSVTVQEGLC VSVLCSFSYPQNGWTASDPV HGYWFRAGDHVSRNIPVATN NPARAVQEETRDRFHLLGDP QNKDCTLSIRDTRESDAGTY VFCVERGNMKWNYKYDQLSV NVTASQDLLSRYRLEVPESV TVQEGLCVSVPCSVLYPHYN WTASSPVYGSWFKEGADIPW DIPVATNTPSG |
| Tissue Specificity | Isoform Short is highly expressed in spleen, small intestine and adrenal gland.it is lower expressed in thyroid, placenta, brain, stomach, bone marrow, spinal cord and breast. Isoform Long is highly expressed in spleen, small intestine and bone marrow.it is lower expressed in thyroid, placenta, thymus, trachea, stomach, lung, adrenal gland, fetal brain and testis. |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 12Siglec-12Sialic Acid-Binding Ig-Like Lectin-Like 1Siglec-L1 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Sialic Acid-Binding Ig-Like Lectin 12 antibodyAnti-Siglec-12 antibodyAnti-Sialic Acid-Binding Ig-Like Lectin-Like 1 antibodyAnti-Siglec-L1 antibodyAnti-SIGLEC12 antibodyAnti-SIGLECL1 antibodyAnti-SLG antibodyAnti-UNQ9215 antibodyAnti-PRO34042 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
