| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Sialate O-acetylesterase for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SIAE |
| Gene ID: | 54414 |
| Uniprot ID: | SIAE_HUMAN |
| Specificity: | This antibody detects endogenous levels of SIAE at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human SIAE |
| Function | Catalyzes the removal of O-acetyl ester groups from position 9 of the free diacetylated sialate N-acetyl-9-O-acetylneuraminate (Neu5,9Ac2) in the cytosol and of the diacetylated sialate residues of sialylglycoconjugates in the lysosomes (Probable). Together with the sialate-O-acetyltransferase they regulate the balance of acetylated sialoglycoconjugates, key players in various processes such as cell-cell interactions, host-pathogen recognition, and tumor antigenicity. |
| Protein Name | Sialate O-AcetylesteraseSiaeH-LseSialic Acid-Specific 9-O-Acetylesterase |
| Database Links | |
| Cellular Localisation | Isoform 1: LysosomeIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Sialate O-Acetylesterase antibodyAnti-Siae antibodyAnti-H-Lse antibodyAnti-Sialic Acid-Specific 9-O-Acetylesterase antibodyAnti-SIAE antibodyAnti-YSG2 antibody |
Information sourced from Uniprot.org
